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Heart failure (HF) is a major cardiovascular complication of T2DM, with affected individuals having an approximately 1.6 to 2-fold higher risk of incident HF than those without diabetes [4]

Cardioprotective and Vasodilatory Actions of Glucagon-Like Peptide 1 Receptor Are Mediated Through Both Glucagon-Like Peptide 1 ReceptorDependent and Independent Pathways

Research like this is why, in January 2025, the FDA approved Ozempic the brand name version of semaglutide for type 2 diabetes to reduce the risk of complications in people who have both type 2 diabetes and kidney disease

"Well, how do we get them in our body

This knowledge informs whether continuous therapy is essential or whether structured maintenance protocols might suffice

This review is the first of two that summarise these advances, with Part I focusing on HF prevention and detection