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In the manufacturing process of HyperHEP B, there are several steps with the capacity for viral inactivation or removal.(1) The main steps of the manufacturing process that contribute to the virus clearance capacity are as follows: To provide additional assurance of the pathogen safety of the final product, the capacity of the HyperHEP B manufacturing process to remove and/or inactivate viruses has been demonstrated by laboratory spiking studies on a scaled down process model using a wide range of viruses with diverse physicochemical properties

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The future trajectory of HAGSH research lies in the convergence of materials science , artificial intelligence , and digital biosensing , leading toward the development of intelligent , self-regulating scaffolds capable of autonomous diagnosis and adaptive treatment

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PMID: 34506029

For microscope examination at 400 magnification under a phase contrast microscope, 500 spermatozoa per group were classified as viable spermatozoa with intact acrosome stained with pink and non-viable spermatozoa with damaged acrosome stained with dark blue or lavender