As for W303-1b/gsh1/pro1 or W303-1b/gsh1/proB, the overexpression of introduced Pro1 or ProB under the control of strong constitutive GAP promoter might allow a small amount of GSH in the host strains conferring tolerance to oxidative stress
To capture global transcriptomic changes associated with distinct ECM environments and to identify gene signatures linked to MC differentiation, plasticity, and other relevant pathways, we analyzed the expression of MITF target genes, MC-specific genes, and broader signaling networks that are associated with the phenotypic shifts observed across ECM conditions
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K.DutschmannM
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Karczewski, K