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Moreover, patients without preexisting conditions, such as moderate-to-severe CKD and chronic ischemic heart disease, showed more pronounced risk reductions (HR = 0.69 and HR = 0.66, respectively) than their counterparts (HR = 0.75 and HR = 0.80, respectively)

Jiangsu Hengrui Pharmaceuticals and Kailera Therapeutics report positive topline data from 8 mg dose of phase 2 obesity trial of GLP-1/GIP receptor dual agonist HRS9531

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The aim of this study was to evaluate whether colistin can directly induce mitochondrial toxicity and, if so, uncover the underlying molecular mechanism