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Real-world effectiveness studies support these clinical trial findings

Six participants were included in the ITT but excluded from the per-protocol (PP) analysis because they did not satisfy the definition of full adherence and therefore did not meet the conditions to be included in PP analysis

However, microdosing is considered an off-label practice with limited clinical research, and professional organizations including the American Diabetes Association do not formally endorse it

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Once antibodies form, each subsequent injection triggers a more targeted immune response at the injection site