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The receptor's large, complex binding surface, characteristic of class B GPCRs, was thought to require the extensive contact area that only a peptide could provide

A., Serotonin SyndromeA Focused Review, Basic & Clinical Pharmacology & Toxicology 133, no

Weeks 5-12 (dose escalation)

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Therefore, as opposed to Prx3, Prx5 has been viewed mainly as a cytoprotective antioxidant enzyme rather than as a redox sensor and appears to be a unique Prx exhibiting specific functional and structural feature (Knoops et al., 2011

The benefits of taking folate with vitamin B12 extend beyond preventing neural tube defects