Most people tolerate B12 well, even at high doses, as excess amounts are excreted through urine
It also has a role in producing red blood cells, as well as sex- and stress-related hormones
Changing or adjusting a dose for your cat on your own without consulting with a veterinarian can carry risk
Fatigue is listed as a common adverse reaction in FDA prescribing information, occurring in 5% or more of patients taking Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide), with higher frequency than placebo in clinical trials
Age-related decline in gastric acid production and intrinsic factor availability may reduce the bodys ability to absorb oral B12 and other nutrients, making IM delivery a practical alternative
When joint aches do occur temporally alongside B12 therapy, they are more likely coincidental or related to other factors rather than a direct pharmacological effect of the vitamin itself