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Journal of Investigative Medicine, 70(1), p.jim-2021-001952

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In the most recent Phase 3 trial, participants on the 12 mg dose lost an average of 28.7% of their body weight at 68 weeks

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Weibull distribution modeling characterized failure patterns of time-to-onset data, where the shape parameter () defined three scenarios: the upper limit of 95% confidence interval (CI) of 1 (wear-out failure: risk escalation with prolonged use) 22 (Table S4)

You may feel an abrupt on/off racing heartbeat, sometimes with chest tightness, shortness of breath, or lightheadedness