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Furthermore, the KDIGO 2024 guidelines cover combination therapy from the perspective of SGLT2is being first-line therapy, and long-acting GLP-1 RAs being an add-on in adults with CKD and T2D who have not achieved individualised glycaemic targets despite use of metformin and SGLT2is, or who are unable to use those medications [2]

Circulating resistin levels in relation with insulin resistance, inflammatory and endothelial dysfunction markers in patients with type 2 diabetes and impaired fasting glucose

This distinction matters because tesamorelin has body composition relevance, but it should not be marketed as a general fat-loss peptide

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