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(4) defense against oxidative stress through activation of FOXO and mammalian nuclear factor erythroid-derived 2 (NEF2l2, also known as Nrf2) transcription factors

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NAD + deficiency accelerates aging Multiply evidence elucidates that NAD + and NAD + -related metabolites govern biological functions in aging, including metabolism, redox homeostasis, mitochondria function and the circadian clock

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Glutathione is a powerful antioxidant made from three amino acids (including glutamine) that protects cells from damage and supports liver detoxification