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Some GLP-1 medications also act on another hormone pathway called GIP (glucose-dependent insulinotropic polypeptide)
GLP-1 helps the pancreas release insulin when blood sugar rises and reduces the amount of glucose released by the liver
Imaging and biomarker panels are used to characterize shifts in body composition alongside weight trajectories
In 2024, it was also approved to Zepbound treat obstructive sleep apnea in adults with obesity
"Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to Basal Insulin Alone or Basal Insulin in Combination With Metformin in Subjects With Type 2 Diabetes (SUSTAIN 5)"
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