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When these signals exceed the detoxification capacity of the liver, they may spill over into the systemic circulation, thereby propagating pathological cascades to peripheral organs

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Autologous fat transfer National consensus survey: trends in techniques for harvest, preparation, and application, and perception of short- and long-term results [J]

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559 Recent studies show that PPAR stimulation leads to hepatocyte hypertrophy in the pericentral region and increased proliferation in the periportal region, promoting liver repair in a YAP/TEAD-dependent manner after PHx

It reduces hepatic steatosis and inflammation, restores gut microbiota balance, and activates the FXR pathway