The SURMOUNT findings are particularly important for people using tirzepatide primarily for weight loss rather than blood sugar control
Methods in dynamic treatment regimens using observational healthcare data: a systematic review
Diabetologia 52(10):20462055 Schirra J, Gke B (2005) The physiological role of GLP-1 in human: incretin, ileal brake or more
Switching to next-generation medications Rather than cycling between existing options, the rapidly evolving GLP-1 landscape offers genuinely new medications that may better serve people who have plateaued on semaglutide or tirzepatide
Patients treated with Ozempic were 24% less likely to develop kidney failure (dialysis, transplantation, or an eGFR of 50% decline), or death from kidney-related or cardiovascular causes Non-alcoholic fatty liver disease (NAFLD), aka metabolic dysfunctionassociated steatohepatitis (MASH), often goes undetected but is closely linked with obesity and metabolic dysfunction
It can also be used for energy metabolism, in the synthesis of other amino acids and to make D-Aspartic Acid, which functions as a neurotransmitter
