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Stay hydrated, sip fluids throughout the day rather than drinking large volumes at once

The FDA has made similar observations at Empower in the past, according to an inspection report from 2023

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Chem Biol 10:233239 Li F, Tang S-C (2017) Targeting metastatic breast cancer with ANG1005, a novel peptide-paclitaxel conjugate that crosses the blood-brain-barrier (BBB), vol 4

Side Effect Mitigation The primary motivation for microdosing is reducing adverse effects: Theoretical advantages: Lower peak concentrations reduce nausea intensity Gradual exposure allows GI adaptation Reduced gastroparesis severity Better maintenance of normal eating patterns 2