This premise is based on the notion that subzero temperatures in supercooled storage can substantially slow down metabolism to mitigate the metabolic storage lesion and thus extend storage time
Dimidi E, Zdanaviciene A, Christodoulides S, et al
Human Equivalent Dose Calculations Using standard conversion formulas accounting for body surface area differences between species, a rat oral dose of 0.0045 mg/lb translates to approximately 0.00073 mg/lb in humans, yielding roughly 0.112 mg/day for a 154-pound person
In addition, there was an increase in MDA, the most general byproduct of lipid peroxidation (Figure 4D)
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no cortisol/prolactin changes at GH-effective concentrations Jimenez-Reina et al