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Mechanism of Action Melanogenesis Stimulation: Activation of MC1R stimulates the synthesis and release of eumelanin (the protective, dark pigment, typically black/brown), as opposed to pheomelanin (the red/yellow pigment)

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Navarro-Yepes J, Burns M, Anandhan A, Khalimonchuk O, Del Razo LM, Quintanilla-Vega B et al (2014) Oxidative stress, redox signaling, and autophagy

Bei diagnostiziertem GH-Mangel (Stimulationstest + IGF-1) bleibt der einzige legale Weg das zugelassene Somatropin

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doi: 10.1186/s40478-020-01031-3 148 SchillingSChausseBDikmenHOAlmouhannaFHollnagelJOLewenAet al