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Among these Lactobacilli strains, L

AEA is an endocannabinoid, exhibiting proinflammatory activity as it was found to exacerbate endotoxin-induced uveitis, enhancing the clinical score of intraocular inflammation and increasing the amount of leukocyte and protein concentration in the aqueous humor [46]

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Additionally, research using PD models has shown that unusually elevated levels of TNF- and interferon-gamma (IFN-) secretion support the TNF-/Janus kinase/signal transducer and activator of transcription and IFN-/MAPK/extracellular signal-regulated kinase-mediated activation of nuclear factor kappa-B in microglia and astroglia, respectively