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Monitoring and Prevention Strategies During GLP-1 Treatment Preventing gallstones while taking semaglutide or tirzepatide involves three practical steps: gradual dose escalation, adequate hydration and dietary fat intake, and scheduled ultrasound screening if you have risk factors

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A semaglutide injection on the same day every week, in a healthy rotated site, at the right depth, is what produces steady blood levels

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Schedule: Daily subcutaneous injections at bedtime for 36 months (pediatric trials ran 612 months