Intracellular production of OH from H 2 O 2 is driven by the Fenton reaction, shown in Reaction 3 ( As the most reactive known ROS, OH reacts with nearly all intracellular building blocks and macromolecules (amino acids, nucleic acids, phospholipids, sugars, proteins, RNA, DNA, lipids, polysaccharides)
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Inagi et al., 2010)
Functional Medicines Approach to Gut Health Functional medicine views the body as an interconnected system
Foods high in polyphenols (e.g., berries, dark chocolate, tea) and prebiotic fibers (e.g., asparagus, chicory root, Jerusalem artichoke) also support Akkermansia
utilizing these values can also help distinguish B12 deficiency from folate deficiency (with folate deficiency, MMA will be normal and homocysteine will be elevated) (6) Levels less than 200 pg/mL are considered deficient (2) Once deficiency is confirmed, it is important to address underlying etiology