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Based on this comprehensive proteomics analysis, MCF7-DoxyR cells show severe reductions in mitochondrial proteins, both those encoded by mitochondrial DNA (mt-DNA) and those encoded by nuclear DNA (nuc-DNA)

Caused by an excess of melanin (the stuff that produces your natural skin color), Dyspigmentation is simply areas of skin that are darker or lighter in color than the rest of your skin

DOI:10.4103/1673-5374.320969