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One is by up-regulating a signaling protein called VEGF (vascular endothelial growth factor), which encourages the growth of new capillaries
While the promise of ozone therapy in contexts such as wound healing in diabetic foot ulcers is evident [80, 85], the call for high-quality randomized controlled trials (RCTs) reverberates, especially when venturing beyond specific wound types
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[1] These effects are typically dose-dependent, most pronounced during dose escalation, and tend to diminish over time