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Furthermore, the mechanism underlying GBA communication involves neuro-immune-endocrine mediators

Furthermore, NADPH is replenished by the isocitrate dehydrogenase (IDH1/IDH2) branch of the citric acid cycle (TCA cycle), malic enzyme (ME1), and one-carbon metabolism (such as the folate cycle) depending on cell type or nutritional status

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They have more subsurface material waiting to be cleared