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152 Potential mechanisms for this action are suppression of cholesterol synthesis by inhibition of the HMG-CoA reductase enzyme or an increase in the rate of LDL degradation

The Q141K mutation is also linked with this phenotype of renal uric acid overload, both in patients who are homozygous for Q141K and those who are heterozygous for Q126X and Q141K

See also References for pregnancy information Cerner Multum, Inc

Pre-existing conditions can change the risk-benefit calculation

Translating enzymology into metabolic regulation: the case of the 2- Oxoglutarate dehydrogenase multienzyme complex

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