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GLP-1 is a hormone secreted by the intestines in response to food intake

If borne out in additional, larger trials, the finding could see the end of a decades-long effort to find a therapy for Parkinsons that could offer a neuroprotective effect, rather than simply treating symptoms like muscle tremors

During lead optimization, less-sensitive cell assays are valuable for distinguishing the contributions of affinity and efficacy in the cellular response to an agonist ( 29 )

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Semaglutide is a tool, not a magic wand

A reduction in insulin-stimulated glucose uptake was observed in PA-treated L6 cells, confirming IR