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Studies show that NNMT inhibition by 5-amino-1-methylquinolinium significantly reduces nicotinamide metabolism, increases NAM accumulation, improves NAD+ synthesis efficiency by over 30%, and markedly increases mitochondrial ATP production and cellular energy metabolism

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Oxidative stress markers have been localized in the follicular fluid in patients undergoing IVF/embryo transfer (ET) [4, 51, 154, 155]

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