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10.1038/nature11400 Nature 28 ChristensenM.VedtofteL.HolstJ

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By contrast, our work, which focuses on active comparators (GLP1-RAs or SGLT2i vs DPP-4i, and head-to-head), demonstrated a reduction in VTE risk for both GLP1-RAs and SGLT2i compared with DPP-4i, and no significant difference between the two newer drug classes, although estimates were imprecise

The anti-apoptotic activity of TB-500 may involve the reduction of early cell death initiation signals and activation of the survival kinase Akt through complex formation with PINCH and integrin-linked kinase

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