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By reducing weight, even modest amountspeople in the semaglutide arm lost about 9% of their body weight over two years in this studywe are reducing the filtering load on the kidneys

Figure 4 illustrates the key mitochondrial antioxidant defense systems against ROS

FDA-approved GLP-1 medications such as Wegovy and Zepbound are considered safe for most patients when prescribed and monitored appropriately

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Exerts potent anti-inflammatory effects in the gut and CNS by modulating nitric oxide pathways and reducing pro-inflammatory cytokines, closely resembling the protective actions of the native gastric peptide in response to mucosal injury

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