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Extensive Clinical Application of GLP-1RAs GLP-1RAs for the Treatment of T2DM GLP-1RAs are well established for the management of T2DM, and their clinical efficacy has been extensively investigated and validated

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1,56 (DCX is a microtubule-associated protein that is expressed by neuronal precursor cells and immature neurons in embryonic and adult cortical structures while actively dividing, with neuronal daughter cells continuing to express DCX for 23 wk as the cells mature into neurons.) Oxidative stress, a common feature in several neurodegenerative conditions, plays a key contributory role in the progressive nature of diseases like PD and AD as well as in acute disorders such as stroke and traumatic brain injury (TBI)

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Particularly relevant for GLP-1 users, L-theanine has been shown to improve glucose tolerance and insulin sensitivity