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doi: 10.1016/j.phymed.2015.01.010, 59

These predispositions do not predict exact medication response or determine candidacy alonemedical history, contraindications, and current health status remain the primary determinants of safety and eligibility

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Use of stomach acid-resistant capsules (DRcaps) further protect stability

Starting at a therapeutic dose on day one would make most people miserable

[11] [12] Symptoms include excessive thirst, frequent urination, nausea, abdominal pain, confusion, and fruity-smelling breath