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World J Surg

| BPC-157, as a healing peptide, refers to a synthetic pentadecapeptide made up of 15 amino acids, derived from a protective protein found in human gastric juice

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Decreasing solvent dielectric strength by addition of cosolutes such as glycerol, sucrose, and ethanol to a protein solution leads to significantly lower rates of isomerization and deamidation (39,44)

The mechanism by which DSIP influences sleep architecture may involve effects on hypothalamic sleep regulatory centers, interactions with circadian clock mechanisms, or modulation of homeostatic sleep drive