These medicines are prescribed in clinical care to support weight management and metabolic health for people living with obesity or related conditions
Therefore glucose metabolism needs to be closely monitored and treated in patients with pituitary adenomas
2025 May;46(5):422-436
It states that these medicines caused thyroid C-cell tumors in rodents, that it is unknown whether they cause similar tumors in humans including medullary thyroid carcinoma, and that the drug is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or with Multiple Endocrine Neoplasia syndrome type 2
Neal B, Perkovic V, Mahaffey KW, de Zeeuw D, Fulcher G, Erondu N, Shaw W, Law G, Desai M, Matthews DR
While there have been improvements in survival over the last decade, progress has been incremental and the mortality rate remains the highest amongst solid malignancies (5-year survival rate of 13%) 2