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The global peptide therapeutics market was valued at over $40 billion USD in 2024 and is projected to surpass $70 billion by 2030 , driven by breakthroughs in obesity treatment, metabolic disease, oncology, and regenerative medicine

Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence

This low-grade systemic inflammation: Impairs insulin receptor signalling, directly worsening insulin resistance Damages ovarian granulosa cells, impairing egg development and ovarian function Disrupts gut barrier integrity, contributing to what some researchers call a "leaky gut" pattern associated with systemic inflammation Amplifies HPA axis dysregulation, raising cortisol and further disrupting sex hormone balance Chronic inflammation is both a consequence of PMOS and a driver that perpetuates it

TABLE 5 Pharmacological effects of catalpol in diabetes

These effects may be optimally stimulated at lower concentrations where the body interprets the signal as a gentle prompt rather than an emergency