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These phenomena lead to biased agonism, which is commonly observed when GLP-1R agonists are assessed across multiple signalling pathways

It is important to distinguish between medication-related effects and those attributable to underlying conditions, lifestyle factors, or psychological responses to body composition changes

We and several of our colleagues have studied the new weight loss drugs, known as GLP-1s, like Wegovy (semaglutide) and Zepbound (tirzepatide), and modeled their impact

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