The Agencys Core Contentions The FDAs press release and the accompanying letters highlight three primary violations: The Agency is aggressively challenging claims that compounded versions contain the same active ingredient as the innovator drugor any other number of ways of saying, expressly or impliedly, that their unapproved compounded product is the same as or similar to those of the innovator manufacturers
Risk of Overdose and Contamination Self-administering smaller doses carries the risk of overdose if a patient miscalculates or adjusts the dose incorrectly
Reactive chemical forms, such as free radicals, can oxidize low-density lipoproteins producing oxy-cholesterols and oxidized fats and proteins within developing arterial plaques
An afternoon nap, especially in the context of a sleep deficit, can effectively relieve fatigue, suppress the sleep drive, and improve cognitive function for hours
References Ludwig MQ, Coester B, Gordian D, et al
They also ran flow cytometry (Annexin V/PI staining) and western blot analysis to measure specific survival and death markers: Bcl-2, Bax, caspase-3, and PARP
