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Clinical, epidemiologic, and virologic studies in four clusters of the chronic fatigue syndrome

The resulting intracellular cholesterol buildup triggers mitochondrial dysfunctionevidenced by diminished ATP synthesis, elevated ROS, and compromised mitochondrial membrane potentialwhich collectively activate HSCs and promote fibrogenesis (104)

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Moreover, the higher milk production largely contributes to a better performance of the suckling piglets (Figure 1)