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By systematically reviewing the neurotoxic mechanisms, clinical manifestations, and therapeutic interventions associated with these six drugs, this study aims to provide insights into the current knowledge gaps and potential avenues for future research

[1] [3] A family of histone deacetylases known as sirtuins (Sirt 1-7) controls a number of proteins involved in cellular metabolism, stress responses, circadian rhythms, and endocrine functions

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Therefore, we hypothesized that the 3 UTR of the IGF-1 gene may be targeted for downregulation by miRNAs in NK cells, leading to attenuation of their cytotoxicity