The trial proceeded without reported toxicity, and no lethal dose threshold (LD1) was ever established in subsequent safety testing meaning researchers administering the compound could not find a dose that caused death in even 1% of test subjects across the animal model safety work that preceded and followed the human study
Dejgaard TF, Johansen NB, Frandsen CS, et al
Thosani N, Singh H, Kapadia A, Ochi N, Lee JH, Ajani J, Swisher SG , Hofstetter WL, Guha S, Bhutani MS Diagnostic accuracy of EUS in differentiating mucosal versus submucosal invasion of superficial esophageal cancers: a systematic review and meta-analysis
"Pelvic floor: anatomy and function"
Doses above 1.5mg produce nausea in 5070% of subjects regardless of receptor sensitivity
Yiangou, Y