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Dietary Restriction (DR ***p0.001, **p0.01, *p0.05Source: WuXi AppTec Internal Data Additionally, the efficacy of semaglutide in a rat MASH model induced by a choline-deficient high-fat diet (CDHFD) was evaluated

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55 CONCLUSION This scoping review provides valuable insights into the complex relationship between GLP-1 agonists and psychiatric comorbidities, and further well-designed, long-term, and standardized studies are needed to clarify the mechanisms, dosage-effect relationships, and potential clinical applications of GLP-1 agonists in the field of mental health

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