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This includes the peptide and CTR (including the ECD position) that adopt the same conformation to those observed in Cagri-bound AMYR-Gs complexes, assessed by overlaying the backbones of the structures (Fig

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Trends Endocrinol Metab 2019;30:701-9.ArticlePubMed 104

As food intake and body weight are controlled by the central nervous system (CNS), understanding the complex CNS mechanisms that regulate energy homeostasis is essential for the discovery of successful antiobesity therapeutics