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However, interpreting the health benefits of selenium against radiotherapy as the clinical validation of the radio-modulating activity of seleno-GPxs may be misleading, since selenium can manifest its beneficial effects through various mechanisms including but not limited to seleno-GPxs

Studies suggest that evaluation of anti-aging compounds often involves co-treatment with retinol to assess inflammatory, hydration, proliferation, and barrier-related markers

Zinc is vital for skin repair , collagen formation, and a healthy inflammatory response

Mercury is among the most toxic metals and an ubiquitous contaminant of the environment, due to its release from mining, from the combustion of fossil fuels, from industrial uses which are now being progressively restricted [86] and from other human activities such as artisanal exploitation of low-grade gold ores

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