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Melanin is produced by cells called melanocytes, controlled by an enzyme called tyrosinase

Under basal, unstressed conditions, their levels are kept low due to targeted degradation by the proteasome

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Signal Transduct Target Ther 5(1):209 Zhou P, Hua F, Wang X, Huang JL (2020a) Therapeutic potential of IKK- inhibitors from natural phenolics for inflammation in cardiovascular diseases

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