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Am J Clin Oncol

CD4 + , CD8 + , and T cells drive inflammation and activate HSCs, which in turn regulate T cell differentiation and proliferation

Members of this family were first discovered for their potential of metabolizing an array of toxic exogenous compounds, i.e., xenobiotics via GSH conjugation (Nianiou-Obeidat et al., 2017)

Busserolles J, Mazur A, Gueux E, Rock E, Rayssiguier Y

J.KoudstaalP

Despite the redundancy accorded to this system by the continued production of JNK2, it appears reasonable to conclude that the JNK1 signaling pathway may be playing a role in T-cell receptor initiated Th cell proliferation, differentiation or apoptosis