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The treatment must be an add-on therapy to optimal standard treatment, which must include, unless contraindicated or cannot be tolerated, a beta blocker and angiotensin converting enzyme inhibitor (ACEi) or angiotensin receptor blocker or angiotensin receptor-neprilysin inhibitor

doi: 10.1021/tx00039a017

Understanding the interaction between B12 and iron is key for effective treatment

If a drug is not on a formulary, a person can speak with an insurer directly to ask if they can provide coverage, which they may do if they consider it medically necessary

The typical formulation contains semaglutide at 5 mg/mL, glycine at 5 mg/mL, and cyanocobalamin (vitamin B12) at 1 mg/mL