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Super physiologic levels of B12 I'd personally risk versus not enough as so much not understood

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Variations in the MTHFR gene can affect how the body metabolises B vitamins, including B12

Serious vitamin B12 deficiency may result in anemia, stomach problems, and nerve damage

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Immunization of Trianni mice and generation of antigen-specific B-cell repertoires Antigen A-DTA-his and Antigen B-DTA-his were prepared in phosphate-buffered saline (PBS) at 1 mg/mL