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Dietary Deficiency: If your deficiency was purely due to diet (e.g., a vegan not supplementing) and youve since adjusted your diet or started regular oral supplements, you might eventually be able to space out injections more or even switch to oral maintenance, though this should always be carefully managed by your GP

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This protease-driven nerve activation is now believed to be a major contributor to the visceral hypersensitivity and widespread "nociplastic" pain seen in conditions like irritable bowel syndrome (IBS), ME/CFS, and fibromyalgia