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2 Although the number of glucose-lowering agents available to treat T2DM has increased dramatically over the past 10 years, gaps continue to exist in care and outcomes

Uric acid-lowering therapy with benzbromarone in hypertension with asymptomatic hyperuricemia: a randomized study focusing left ventricular diastolic function

Phase 1 trial data included groups that started directly at higher doses, and while efficacy was not compromised, GI side effect rates nearly doubled compared to the gradual approach

Finally, prebiotics might be implicated in diminishing adipogenesis, via inhibiting the endocannabinoid system in the gut and adipose tissue (60, 66)