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The good news is that these issues mostly occur in the beginning weeks while your body is getting used to taking this GLP-1 medication

Precautions and side effects Watch out for possible side effects such as skin reactions and severe abdominal pain

Summary: Thirst is not a recognised adverse effect of Rybelsus according to UK prescribing information, though some patients may experience it due to hyperglycaemia, dehydration from gastrointestinal side effects, or inadequate fluid intake

Semaglutide reduces vascular inflammation investigated by PET in a rabbit model of advanced atherosclerosis