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Murphy and George Minot for discovery of an effective treatment for pernicious anemia using liver concentrate, later found to contain a large amount of vitamin B 12
Reviews of the rodent work note that the mechanism doesnt involve the hormonal suppression or receptor desensitization that would predict tolerance or rebound, and that adipose SAM levels tend to normalize rather than crash under inhibition
Injectable vitamin B12, which can treat significant deficiencies, may cause the following common side effects: More serious side effects of vitamin B12 injections can include: irregular heartbeat heart palpitations hives or a skin rash Vitamin B12 can cause very rare but serious allergic reactions, or anaphylaxis
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