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The difference is driven by retatrutide's triple mechanism (GLP-1 + GIP + glucagon) vs Foundayo's single GLP-1 mechanism

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It is also explored for its role in maintaining strong immune response through support of white blood cell activity

Evidence from the National Weight Control Registry, which tracks individuals who have maintained significant weight loss long-term, provides valuable insights into effective strategies, though these findings are observational

doi:10.2307/1369559