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The study population had an estimated baseline coronary heart disease risk of 11.6% over 10 years based on the Framingham risk criteria and included a high percentage of patients with additional risk factors such as hypertension (58%), low HDL-C levels (23%), cigarette smoking (16%), or a family history of premature CHD (12%)

They are activated by TLR and danger signals, and can extrude DNA and antimicrobial peptides, which can lead to dendritic cell activation in psoriasis

doi:10.1073/pnas.0408819102

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five of which injected the liver with the drug at 150 mg per kg intraperitoneally

Collectively, these trials demonstrated convincing glycemic control in diabetics